Preisträger 2015
Haifeng Xu
Education
2006-2010 Honours Bachelor of Science, Department of Immunology, University of Toronto, Toronto, Canada.
2010-2015 Doctoral Thesis, Institute of Immunology, University of Duisburg-Essen, Germany.
Advisor: Prof. Dr. Karl S. Lang.
Co-advisor: Prof. Dr. Philipp A. Lang (Department of Gastroenterology, Hepatology, and Infectious Diseases, Heinrich Heine University, Düsseldorf, Germany. Director: Prof. Dr. med. Dieter Häussinger).
Thesis topic: Innate immune functions during viral infection.
Selected publications
Xu HC*, Huang J*, Khairnar V, Duhan V, Pandyra AA, Grusdat M, Shinde P, McIlwain DR, Maney SK, Gommerman J, Löhning M, Ohashi PS, Mak TW, Pieper K, Sic H, Speletas M, Eibel H, Ware CF, Tumanov AV, Kruglov AA, Nedospasov SA, Häussinger D, Recher M, Lang KS, Lang PA.
Deficiency of the B cell-activating factor receptor results in limited CD169+ macrophage function during viral infection.
J Virol. 2015 May;89(9):4748-59.
*shared authorship
Xu HC*, Grusdat M*, Pandyra AA, Polz R, Huang J, Sharma P, Deenen R, Köhrer K, Rahbar R, Diefenbach A, Gibbert K, Löhning M, Höcker L, Waibler Z, Häussinger D, Mak TW, Ohashi PS, Lang KS, Lang PA.
Type I interferon protects antiviral CD8 T cells from NK cell cytotoxicity.
Immunity. 2014 Jun 19;40(6):949-60.
*shared authorship
Lang PA*, Xu HC*, Grusdat M, McIlwain DR, Pandyra AA, Harris IS, Shaabani N, Honke N, Kumar Maney S, Lang E, Pozdeev VI, Recher M, Odermatt B, Brenner D, Häussinger D, Ohashi PS, Hengartner H, Zinkernagel RM, Mak TW, Lang KS.
Reactive oxygen species delay control of lymphocytic choriomeningitis virus.
Cell Death Differ. 2013 Apr;20(4):649-58.
*shared authorship
McIlwain DR, Lang PA, Maretzky T, Hamada K, Ohishi K, Maney SK, Berger T, Murthy A, Duncan G, Xu HC, Lang KS, Häussinger D, Wakeham A, Itie-Youten A, Khokha R, Ohashi PS, Blobel CP, Mak TW. iRhom2 regulation of TACE controls TNF-mediated protection against Listeria and responses to LPS. Science. 2012 Jan 13;335(6065):229-32.
Lang PA, Lang KS, Xu HC, Grusdat M, Parish IA, Recher M, Elford AR, Dhanji S, Shaabani N, Tran CW, Dissanayake D, Rahbar R, Ghazarian M, Brüstle A, Fine J, Chen P, Weaver CT, Klose C, Diefenbach A, Häussinger D, Carlyle JR, Kaech SM, Mak TW, Ohashi PS.
Natural killer cell activation enhances immune pathology and promotes chronic infection by limiting CD8+ T-cell immunity.
Proc Natl Acad Sci U S A. 2012 Jan 24;109(4):1210-5.